After being informed of a potential microduplication in Figure 1D, the journal contacted the authors for clarification. The ...

Although the Arabidopsis thaliana RPD3-type histone deacetylase HDA19 and its close homolog HDA6 participate in SIN3-type histone deacetylase complexes, they display distinct biological roles, with ...

Stabilization of microtubule plus end-directed kinesin CENP-E at the metaphase kinetochores is important for chromosome alignment, but its mechanism remains unclear. Here, we show that CKAP5, a ...

Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

N6-methyladenosine (m 6 A) exerts many of its regulatory effects on eukaryotic mRNAs by recruiting cytoplasmic YT521-B homology-domain family (YTHDF) proteins. Here, we show that in Arabidopsis ...

Spatial metabolomics is transforming our understanding of microbial systems by uncovering the localized molecular dynamics ...

Copine-6 is a calcium-sensitive phospholipid-binding protein of the evolutionarily conserved Copine family. In the central nervous system, Copine-6 regulates function of some neurotransmitter ...

Synaptic long-term potentiation (LTP) involves generation of myristic acid from synaptic membrane phospholipids via the activity of the phospholipase A1 DDHD2. This work shows that myristic acid ...

We demonstrate that TP53 deficiency in AML cells confers resistance to CAR T-cell therapy by inducing CAR T-cell dysfunction. We propose a model in which difficult-to-kill TP53 -mutant AML cells ...

The three-dimensional (3D) chromatin structure of Epstein–Barr virus (EBV) within host cells and the underlying mechanisms of chromatin interaction and gene regulation, particularly those involving ...

DarT is present in many bacteria and, in some, an orthologous system, DarT1, is also present, catalysing ADP-ribosylation of guanosine bases in ssDNA (Cihlova et al, 2024; Schuller et al, 2023). In ...